Erlotinib Hydrochloride

• Background:

  Erlotinib Hydrochloride inhibits the human epidermal growth factor receptor (HER-1/EGFR) tyrosine kinase.

• Description:

  EGFR Kinase inhibitor

• Product Name Alternative:

  N- (3-ethynylphenyl) -6,7-bis (2-methoxyethoxy) quinazolin-4-amine hydrochloride

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity:

  ≥99%

• Weight:

  0.1

• Format:

  Solid powder

• Solubility:

  Soluble in DMSO at 18 mg/ml with warming; very poorly soluble in ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-20 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility

• Molecular Formula:

  C22H24ClN3O4

• Molecular Weight:

  429.9

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Ali S., et al. (2008) Mol. Cancer Ther. 7(6): 1708–1719.

• CAS Number:

  183319-69-9