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SF-C5-TPP

CAT: 0804-HY-157933Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157933Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SF-C5-TPP is an potent mitochondria-targeted protonophoric uncoupler. SF-C5-TPP has significant proton transfer activity on model planar bilayer lipid membranes. SF-C5-TPP inhibits the growth of Bacillus subtilis with a MIC of 2 μM>[1].
UNSPSC
12352005
Target
Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sf-c5-tpp.html
Solubility
10 mM in DMSO
Smiles
N#C/C(C#N)=C(CCCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)\C4=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C4.[Br-]
Molecular Formula
C41H46BrN2OP
Molecular Weight
693.69
References & Citations
[1]Kirsanov R S, et al. Synthesis of Triphenylphosphonium-Linked Derivative of 3, 5-Di tert-butyl-4-hydroxybenzylidene-malononitrile (SF6847) via Knoevenagel Reaction Yields an Effective Mitochondria-Targeted Protonophoric Uncoupler. ACS Omega. 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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