2'-Hydroxyflavanone

• Description :

  2'-Hydroxyflavanone is a flavanone that can inhibit cancer cell proliferation, induce apoptosis, and reduce inflammation. 2'-Hydroxyflavanone shows inhibitory effect on platelet aggregation caused by two inducers with IC50s 47.8 μM arachidonic acid (AA) and 147.2 μM aenosine diphosphate (ADP) [1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Apoptosis

• Type :

  Natural Products

• Related Pathways :

  Apoptosis

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/2-hydroxyflavanone.html

• Concentration :

  10mM

• Purity :

  99.84

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C1CC(C2=CC=CC=C2O)OC3=CC=CC=C13

• Molecular Formula :

  C15H12O3

• Molecular Weight :

  240.25

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Khaled Alkadi, et al. Antiplatelet aggregation activity of 5-Hydroxyflavone, 2’-Hydroxyflavanone, Paeonol and bergenin isolated from stem bark of Garcinia malaccensis in human whole blood. September 2013Oriental Journal Of Chemistry 29 (03) :871-875

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [17348-76-4]