7-Hydroxyflavanone

• Description :

  7-Hydroxyflavanone is a potent inhibitor of aromatase (CYP19) activity with the IC50 of 65 μM. 7-Hydroxyflavanone exerts various biological effects, including anticarcinogenic, antioxidant and (anti-) estrogenic effects, and modula

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H335

• Target :

  Cytochrome P450

• Type :

  Natural Products

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer; Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/7-hydroxyflavanone.html

• Purity :

  99.59

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  O=C1CC(C2=CC=CC=C2)OC3=C1C=CC(O)=C3

• Molecular Formula :

  C15H12O3

• Molecular Weight :

  240.25

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]Sanderson JT, et al. Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. Toxicol Sci. 2004 Nov;82 (1) :70-9. |[2]J Thomas Sanderson, et al. Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. Toxicol Sci. 2004 Nov;82 (1) :70-9.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, stored under nitrogen)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  Aromatase/CYP19A1

• CAS Number :

  [6515-36-2]