6-Hydroxyflavanone

• Description :

  6-Hydroxyflavanone is a compound that can be isolated from the Muntingia calabura leaves. 6-Hydroxyflavanone targets cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), and opioid and GABA-A receptors that has anti-inflammatory and anti-neuropathic pain potential. 6-Hydroxyflavanone can be used for the research of diabetes[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H335

• Target :

  COX; GABA Receptor; Lipoxygenase; Opioid Receptor

• Type :

  Natural Products

• Related Pathways :

  GPCR/G Protein; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/6-hydroxyflavanone.html

• Purity :

  99.87

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(C1)C(C=C(O)C=C2)=C2OC1C3=CC=CC=C3

• Molecular Formula :

  C15H12O3

• Molecular Weight :

  240.25

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]Zolkeflee NKZ, et al. In Vitro Anti-Diabetic Activities and UHPLC-ESI-MS/MS Profile of Muntingia calabura Leaves Extract. Molecules. 2022 Jan 4;27 (1) :287.|[2]Akbar S, et al. Targeting Anti-Inflammatory Pathways to Treat Diabetes-Induced Neuropathy by 6-Hydroxyflavanone. Nutrients. 2023 May 30;15 (11) :2552.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [4250-77-5]