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6-Hydroxyflavanone

CAT: 0804-HY-W028263-01Size: 250 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W028263-01Size:250 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
6-Hydroxyflavanone is a compound that can be isolated from the Muntingia calabura leaves. 6-Hydroxyflavanone targets cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), and opioid and GABA-A receptors that has anti-inflammatory and anti-neuropathic pain potential. 6-Hydroxyflavanone can be used for the research of diabetes[1][2].
CAS Number
4250-77-5
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
COX; GABA Receptor; Lipoxygenase; Opioid Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/6-hydroxyflavanone.html
Purity
99.87
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1)C(C=C(O)C=C2)=C2OC1C3=CC=CC=C3
Molecular Formula
C15H12O3
Molecular Weight
240.25
Precautions
H315, H319, H335
References & Citations
[1]Zolkeflee NKZ, et al. In Vitro Anti-Diabetic Activities and UHPLC-ESI-MS/MS Profile of Muntingia calabura Leaves Extract. Molecules. 2022 Jan 4;27 (1) :287.|[2]Akbar S, et al. Targeting Anti-Inflammatory Pathways to Treat Diabetes-Induced Neuropathy by 6-Hydroxyflavanone. Nutrients. 2023 May 30;15 (11) :2552.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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