4′-Hydroxyflavone

• Description:

  4′-Hydroxyflavone (compound 50) can inhibit aldose reductase, with IC50 12 μM[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Aldose Reductase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Assay Protocol:

  https://www.medchemexpress.com/4-hydroxyflavone.html

• Purity:

  97.0

• Smiles:

  C1=CC=C2C (=C1) C (=O) C=C (C3=CC=C (C=C3) O) O2

• Molecular Formula:

  C15H10O3

• Molecular Weight:

  238.24

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Michael Fernández, et al. Quantitative structure-activity relationship to predict differential inhibition of aldose reductase by flavonoid compounds. Bioorg Med Chem. 2005 May 2;13 (9) :3269-77.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  RT, protect from light, stored under nitrogen

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  4143-63-9