4′-Hydroxyflavone

• Description :

  4′-Hydroxyflavone (compound 50) can inhibit aldose reductase, with IC50 12 μM[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Aldose Reductase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Assay Protocol :

  https://www.medchemexpress.com/4-hydroxyflavone.html

• Purity :

  97.0

• Smiles :

  C1=CC=C2C(=C1)C(=O)C=C(C3=CC=C(C=C3)O)O2

• Molecular Formula :

  C15H10O3

• Molecular Weight :

  238.24

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Michael Fernández, et al. Quantitative structure-activity relationship to predict differential inhibition of aldose reductase by flavonoid compounds. Bioorg Med Chem. 2005 May 2;13 (9) :3269-77.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  RT, protect from light, stored under nitrogen

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [4143-63-9]