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AOC3 rabbit pAb

CAT: 0855-ES11338-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11338-02Size:100 µL
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Background
This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
Description
This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013],
UniProt
Q16853
Swiss Prot
Q16853
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 510-590
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
83kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
83kD
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass type II membrane protein .
Gene ID (Human)
8639

UniProtKB · Q16853

Amine oxidase [copper-containing] 3

AOC3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q16853
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AOC3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.4.3.21
Processing
—
Secondary accessions
B2RCI5, K7ESB3, L0L8N9, Q45F94
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumCopperMetal-binding

Biological process

Cell adhesion

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinTPQ

Molecular function

Oxidoreductase

Domain

Signal-anchorTransmembraneTransmembrane helix

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