PRLR rabbit pAb

CAT: 0855-ES11315-02Size: 100 µLDry Ice: NoHazardous: No

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CAT#:0855-ES11315-02Size:100 µL

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Background

This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]

Description

This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I Cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011],

UniProt

P16471

Swiss Prot

P16471

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 80-160

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

68kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

68kD

Fragment

IgG

Subcellular Location

Membrane ; Single-pass type I membrane protein .; [Isoform 7]: Secreted.

Gene ID (Human)

5618

UniProtKB · P16471

Prolactin receptor

PRLR_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P16471
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: PRLR
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: PRL-R
EC number: —
Processing: Precursor
Secondary accessions: B2R882, D1MDP1, Q16354, Q8TD75, Q8TD78, Q96P35, Q96P36, Q9BX87, Q9UHJ5

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Disease variant

PTM

Disulfide bondGlycoprotein

Cellular component

MembraneSecreted

Ligand

Metal-bindingZinc

Molecular function

Receptor

Domain

RepeatSignalTransmembraneTransmembrane helix

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Alternative Products

Catalog	Name
E47R43100	PRLR Rabbit pAb
GTR17870074	PRLR Rabbit Polyclonal Antibody
MBS5304970-01	Rabbit polyclonal PRLR antibody
E65G1290	PRLR Rabbit Monoclonal Antibody
HY-P87635	PRLR Antibody (YA7319, Rabbit)
SL6445R-01	Rabbit Anti-PRLR antibody
MBS8555814-01	PRLR (Center) Rabbit pAb
GTR18798248-01	PRLR Recombinant Rabbit mAb
P32541-01	Rabbit Polyclonal Antibody to PRLR
GTR18377052	PRLR Rabbit Polyclonal Antibody (FITC)