PRLR rabbit pAb

CAT: 0855-ES11315-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES11315-01Size:50 µL
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Background
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]
Description
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I Cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011],
UniProt
P16471
Swiss Prot
P16471
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 80-160
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
68kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
68kD
Fragment
IgG
Subcellular Location
Membrane ; Single-pass type I membrane protein .; [Isoform 7]: Secreted.
Gene ID (Human)
5618

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