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Internexin-α rabbit pAb

CAT: 0855-ES7963-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7963-01Size:50 µL
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Background
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons. [provided by RefSeq, Jun 2009]
Description
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons. [provided by RefSeq, Jun 2009],
UniProt
Q16352
Swiss Prot
Q16352
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the Internal region of human Internexin-α.
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
55kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
55kD
Fragment
IgG
Subcellular Location
Extracellular space, nucleoplasm, neurofilament, nuclear membrane, cytoplasmic ribonucleoprotein granule, myelin sheath, intermediate filament cytoskeleton
Other Product Names
INA; NEF5; Alpha-internexin; Alpha-Inx; 66 kDa neurofilament protein; NF-66; Neurofilament-66; Neurofilament 5
Gene ID (Human)
9118

UniProtKB · Q16352

Alpha-internexin

AINX_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q16352
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
INA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Alpha-Inx
EC number
—
Processing
—
Secondary accessions
B1AQK0, Q9BRC5
Protein keywords

PTM

AcetylationGlycoproteinPhosphoprotein

Domain

Coiled coil

Molecular function

Developmental protein

Biological process

DifferentiationNeurogenesis

Technical term

Direct protein sequencingProteomics identificationReference proteome

Cellular component

Intermediate filament

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