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KCNQ5 rabbit pAb

CAT: 0855-ES6843-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES6843-01Size:50 µL
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Background
This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Description
This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],
Product Name Alternative
KCNQ5; Potassium voltage-gated channel subfamily KQT member 5; KQT-like 5; Potassium channel subunit alpha KvLQT5; Voltage-gated potassium channel subunit Kv7.5
UniProt
Q9NR82
Swiss Prot
Q9NR82
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human KCNQ5. AA range:637-686
Target
KCNQ5
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Molecular Weight
100-110kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
100-110kD
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein .
Other Product Names
KCNQ5; Potassium voltage-gated channel subfamily KQT member 5; KQT-like 5; Potassium channel subunit alpha KvLQT5; Voltage-gated potassium channel subunit Kv7.5
Gene ID (Human)
56479

UniProtKB · Q9NR82

Potassium voltage-gated channel subfamily KQT member 5

KCNQ5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NR82
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KCNQ5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6NKT6, A6PVT6, A8MSQ5, B4DS33, B5MC83, B7ZL37, F5GZV0, Q17RE1, Q5VVP3, Q86W40, Q9NRN0, Q9NYA6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

Disease

Disease variantIntellectual disability

Molecular function

Ion channelPotassium channelVoltage-gated channel

Biological process

Ion transportPotassium transportTransport

PTM

Phosphoprotein

Ligand

Potassium

Domain

TransmembraneTransmembrane helix

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