Products for Research Use Only
RegisterLogin

KCNQ4 rabbit pAb

CAT: 0855-ES2670-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES2670-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Product Name Alternative
KCNQ4; Potassium voltage-gated channel subfamily KQT member 4; KQT-like 4; Potassium channel subunit alpha KvLQT4; Voltage-gated potassium channel subunit Kv7.4
UniProt
P56696
Swiss Prot
P56696
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human KCNQ4. AA range:644-693
Target
KCNQ4
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Molecular Weight
80kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
80kD
Fragment
IgG
Subcellular Location
Basal cell membrane; Multi-pass membrane protein. Situated at the basal membrane of cochlear outer hair cells. .
Other Product Names
KCNQ4; Potassium voltage-gated channel subfamily KQT member 4; KQT-like 4; Potassium channel subunit alpha KvLQT4; Voltage-gated potassium channel subunit Kv7.4
Gene ID (Human)
9132

Related Products

CatalogName
ES15347-01KCNH4 rabbit pAb
ES10032-01KCNQ1 rabbit pAb
ES10030-01KCNG4 rabbit pAb
ES6843-01KCNQ5 rabbit pAb
ES10029-01KCNE4 rabbit pAb
ES20693-01KCNN4 (SK4) rabbit pAb
EA295-01KCNK4 (TRAAK) Rabbit pAb
EA302-01KCNN4 (SK4) Rabbit pAb
ES20697-01KCNK4 (TRAAK) rabbit pAb
ES6014-01KCNQ2/3/4/5 rabbit pAb

Alternative Products

CatalogName
GTR18606507-01KCNQ4 Rabbit pAb
TA359666KCNQ4 Rabbit Polyclonal Antibody
GTR18051335-01KCNQ4 rabbit pAb Antibody
SL16913R-01Rabbit Anti-KCNQ4 antibody
GTR18391499KCNQ4 Rabbit Polyclonal Antibody (HRP)
PAV8424Rabbit Anti-KCNQ4 Polyclonal Antibody
GTR18391500KCNQ4 Rabbit Polyclonal Antibody (FITC)
GTR18391498KCNQ4 Rabbit Polyclonal Antibody (Biotin)
PA86234HU-01Rabbit Anti-Human KCNQ4 Polyclonal Antibody
MBS8424125-01Rabbit Anti Human KCNQ4 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4)(Western Blot, IHC, ELISA)

Popular Products