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CD240d rabbit pAb

CAT: 0855-ES4356-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4356-02Size:100 µL
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Background
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Description
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Product Name Alternative
RHD; Blood group Rh (D) polypeptide; RHXIII; Rh polypeptide 2; RhPII; Rhesus D antigen; CD240D
UniProt
Q02161
Swiss Prot
Q02161
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from Blood group Rh (D) polypeptide at AA range: 161-210
Target
CD240d
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
45kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
45kD
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein .
Other Product Names
RHD; Blood group Rh (D) polypeptide; RHXIII; Rh polypeptide 2; RhPII; Rhesus D antigen; CD240D
Gene ID (Human)
6007

UniProtKB · Q02161

Blood group Rh(D) polypeptide

RHD_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q02161
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RHD
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q02162, Q07618, Q16147, Q16235, Q16355, Q5VSK0, Q5XLS9, Q5XLT1, Q5XLT2, Q9NPK0, Q9UQ20, Q9UQ21, Q9UQ22, Q9UQ23
Protein keywords

Coding sequence diversity

Alternative splicing

Molecular function

Blood group antigen

Cellular component

Cell membraneMembrane

Technical term

Direct protein sequencingProteomics identificationReference proteome

PTM

LipoproteinPalmitate

Domain

TransmembraneTransmembrane helix

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