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CD242 rabbit pAb

CAT: 0855-ES8799-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES8799-01Size:50 µL
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Background
This gene encodes the Landsteiner-Wiener (LW) blood group antigen (s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW (A) /LW (B) blood group antigens is a single aa variation at position 100; Gln-100=LW (A) and Arg-100=LW (B) . Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Description
This gene encodes the Landsteiner-Wiener (LW) blood group antigen (s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW (A)/LW (B) blood group antigens is a single aa variation at position 100; Gln-100=LW (A) and Arg-100=LW (B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],
UniProt
Q14773
Swiss Prot
Q14773
Reactivity
Human; Mouse
Immunogen
Synthetic peptide from human protein at AA range: 141-190
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
[Isoform Long]: Cell membrane; Single-pass type I membrane protein.; [Isoform Short]: Secreted .; Cell membrane ; Single-pass type I membrane protein .
Other Product Names
Intercellular adhesion molecule 4 (ICAM-4; Landsteiner-Wiener blood group glycoprotein; LW blood group protein; CD antigen CD242)
Gene ID (Human)
3386

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