CD249 rabbit pAb

• Background :

  Catalytic activity:Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide., cofactor:Binds 1 zinc ion per subunit., function:Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells., similarity:Belongs to the peptidase M1 family., subunit:Homodimer; disulfide-linked., tissue specificity:Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.

• Description :

  Catalytic activity: Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide. Cofactor: Binds 1 zinc ion per subunit. function: Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells. similarity: Belongs to the peptidase M1 family. subunit: Homodimer; disulfide-linked. tissue specificity: Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.

• UniProt :

  Q07075

• Swiss Prot :

  Q07075

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from the Internal region of human ENPEP. AA range:671-720

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight :

  110kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  110kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Single-pass type II membrane protein.

• Other Product Names :

  ENPEP; Glutamyl aminopeptidase; EAP; Aminopeptidase A; AP-A; Differentiation antigen gp160; CD249

• Gene ID (Human) :

  2028