CD201 rabbit pAb

• Background:

  The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013]

• Description:

  The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013],

• UniProt:

  Q9UNN8

• Swiss Prot:

  Q9UNN8

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthesized peptide derived from Endothelial protein C receptor at AA range: 141-190

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  26kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  26kD

• Fragment:

  IgG

• Subcellular Location:

  Membrane; Single-pass type I membrane protein.

• Other Product Names:

  PROCR; EPCR; Endothelial protein C receptor; Activated protein C receptor; APC receptor; Endothelial cell protein C receptor; CD201

• Gene ID (Human):

  10544