IGFBP6 rabbit pAb

CAT: 0855-ES4091-02Size: 100 µLDry Ice: NoHazardous: No

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CAT#:0855-ES4091-02Size:100 µL

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Background

Function:IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors., PTM:O-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. Major glycoforms consist of 8-16 monosaccharides (by homology to IGFBP6 expressed recombinantly in CHO cells) ., similarity:Contains 1 IGFBP N-terminal domain., similarity:Contains 1 thyroglobulin type-1 domain.

Description

Function: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. PTM: O-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. Major glycoforms consist of 8-16 monosaccharides (by homology to IGFBP6 expressed recombinantly in CHO cells). similarity: Contains 1 IGFBP N-terminal domain. similarity: Contains 1 thyroglobulin type-1 domain.

Product Name Alternative

IGFBP6; IBP6; Insulin-like growth factor-binding protein 6; IBP-6; IGF-binding protein 6; IGFBP-6

UniProt

P24592

Swiss Prot

P24592

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human IGFBP6. AA range:101-150

Target

IGFBP6

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

25kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

25kD

Fragment

IgG

Subcellular Location

Secreted .

Other Product Names

IGFBP6; IBP6; Insulin-like growth factor-binding protein 6; IBP-6; IGF-binding protein 6; IGFBP-6

Gene ID (Human)

3489

UniProtKB · P24592

Insulin-like growth factor-binding protein 6

IBP6_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P24592
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: IGFBP6
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: IBP-6, IGF-binding protein 6, IGFBP-6
EC number: —
Processing: Precursor
Secondary accessions: Q14492

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoprotein

Molecular function

Growth factor binding

Cellular component

Secreted

Domain

Signal

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