IGFBP6 rabbit pAb

• Background:

  Function:IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors., PTM:O-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. Major glycoforms consist of 8-16 monosaccharides (by homology to IGFBP6 expressed recombinantly in CHO cells) ., similarity:Contains 1 IGFBP N-terminal domain., similarity:Contains 1 thyroglobulin type-1 domain.

• Description:

  Function: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. PTM: O-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. Major glycoforms consist of 8-16 monosaccharides (by homology to IGFBP6 expressed recombinantly in CHO cells). similarity: Contains 1 IGFBP N-terminal domain. similarity: Contains 1 thyroglobulin type-1 domain.

• UniProt:

  P24592

• Swiss Prot:

  P24592

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from the Internal region of human IGFBP6. AA range:101-150

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  25kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  25kD

• Fragment:

  IgG

• Subcellular Location:

  Secreted .

• Other Product Names:

  IGFBP6; IBP6; Insulin-like growth factor-binding protein 6; IBP-6; IGF-binding protein 6; IGFBP-6

• Gene ID (Human):

  3489