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CTPS rabbit pAb

CAT: 0855-ES2070-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2070-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate) . This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Description
This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
UniProt
P17812
Swiss Prot
P17812
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CTPS. AA range:60-109
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
67kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
67kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytosol . Mainly cytosolic but when active detected in long filamentous structures (PubMed:25223282) . Co-localizes with TNK2 in the cytosolic filaments (By similarity) . .
Other Product Names
CTPS1; CTPS; CTP synthase 1; CTP synthetase 1; UTP--ammonia ligase 1
Gene ID (Human)
1503

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