YOK-2204

• UNSPSC Description:

  YOK-2204 is a ligand of p62-ZZ domain. YOK-2204 can activate p62-dependent selective macroautophagy. YOK-2204 can be used for AUTOTAC design[1].

• Target Antigen:

  AUTOTACs; p62

• Type:

  Reference compound

• Related Pathways:

  Autophagy;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/yok-2204.html

• Smiles:

  O[C@H](CNC(C)C)COC1=CC(OCCC2=CC=CC=C2)=C(OCCC3=CC=CC=C3)C=C1

• Molecular Weight:

  449.58

• References & Citations:

  [1]Ji CH, et al. The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system. Nat Commun. 2022 Feb 16;13(1):904.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2409959-99-3