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YOK-1304

CAT: 0804-HY-161739-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-161739-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YOK-1304 is a ligand of p62-ZZ domain. YOK-1304 can activate p62-dependent selective macroautophagy. YOK-1304 can be used for AUTOTAC design[1].
CAS Number
2409960-03-6
UNSPSC
12352005
Target
P62
Type
Reference compound
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/yok-1304.html
Purity
98.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)NC[C@@H](O)COC1=CC(OCCCC2=CC=CC=C2)=C(OCC3=CC=CC=C3)C=C1
Molecular Formula
C28H35NO4
Molecular Weight
449.58
References & Citations
[1]Ji CH, et al. The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system. Nat Commun. 2022 Feb 16;13 (1) :904.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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