Products for Research Use Only
RegisterLogin

QAQ (dichloride)

CAT: 0804-HY-110358-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-110358-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
QAQ dichloride, a photoswitchable voltage-gated Nav and Kv channels blocker, blocks channels in its trans form (of the azobenzene photoswitch), but not in its cis form. QAQ dichloride is membrane-impermeant and only infiltrates pain-sensing neurons that express endogenous import channels. QAQ dichloride acts as a light-sensitive analgesic and can be used for studying of signaling mechanisms in acute and chronic pain[1][2].
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/qaq-dichloride.html
Purity
98.68
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=CC=C(/N=N/C2=CC=C(NC(C[N+](CC)(CC)CC)=O)C=C2)C=C1)C[N+](CC)(CC)CC.[Cl-].[Cl-]
Molecular Formula
C28H44Cl2N6O2
Molecular Weight
567.59
References & Citations
[1]Timm Fehrentz, et al. Exploring the Pharmacology and Action Spectra of Photochromic Open-Channel Blockers. Chembiochem. 2012 Aug 13;13 (12) :1746-9.|[2]Alexandre Mourot, et al.Photochromic Potassium Channel Blockers: Design and Electrophysiological Characterization. Methods Mol Biol. 2013;995:89-105.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-110358AQAQ
HY-W338604Prospidium (dichloride)
HY-W105666PEG2-Dichloride
HY-W034976Decamethylzirconocene dichloride
HY-B1700A-01Mivacurium (dichloride)
HY-136564DAD (dichloride)
HY-106782Titanocene dichloride
HY-W087964-01Dodecanedioyl dichloride
HY-W011108-01Obidoxime (dichloride)
HY-106901A-01Asoxime (dichloride)

Alternative Products

CatalogName
D52250Diphenylselenium dichloride
T30195-01Triphenylantimony dichloride
M01420-01Malonyl dichloride
B6286-50Ambenonium dichloride
FH60619Hafnocene Dichloride
FD60626-01Dimethyltin dichloride
FM39681-01Manganese dichloride
FAA79968Methanedisulfonyl Dichloride
T24692-01QAQ dichloride
E8609-68FEthylphosphoryl Dichloride

Popular Products