Products for Research Use Only
RegisterLogin

QAQ

CAT: 0804-HY-110358ASize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-110358ASize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
QAQ dichloride dichloride, a photoswitchable voltage-gated Nav and Kv channels blocker, blocks channels in its trans form (of the azobenzene photoswitch), but not in its cis form. QAQ dichloride dichloride is membrane-impermeant and only infiltrates pain-sensing neurons that express endogenous import channels. QAQ dichloride dichloride acts as a light-sensitive analgesic and can be used for studying of signaling mechanisms in acute and chronic pain[1][2].
CAS Number
1204416-85-2
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/qaq.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(/N=N/C2=CC=C(NC(C[N+](CC)(CC)CC)=O)C=C2)C=C1)C[N+](CC)(CC)CC
Molecular Formula
C28H44N6O2
Molecular Weight
496.69
References & Citations
[1]Timm Fehrentz, et al. Exploring the Pharmacology and Action Spectra of Photochromic Open-Channel Blockers. Chembiochem. 2012 Aug 13;13 (12) :1746-9.|[2]Alexandre Mourot, et al.Photochromic Potassium Channel Blockers: Design and Electrophysiological Characterization. Methods Mol Biol. 2013;995:89-105.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
CN-A038-500GMAgar, Micropropagation - Type I (Gracilaria)
M2302-20HPhaseShield™ Gel Tubes, Heavy (200x 2ml)
M2302-20LPhaseShield™ Gel Tubes, Light (200x 2ml)
RHD55901Anti-PTGS1 Antibody (R1S27)
RHD55804Anti-TCEA1 Antibody (R1S24)
E-KAB-0614Porcine IL-2 Antibody Pair Set
RHD55803Anti-TCEA1 Antibody (R1S23)
PKSH030904Recombinant Human Purine nucleoside phosphorylase/PNP Protein (His Tag)
PKSH031350Recombinant Human Ficolin-1/Ficolin-A/FCN1 Protein (His Tag)
RHD55701Anti-FBLN1 Antibody (R1S21)

Popular Products