QAQ dichloride

• Target:

  Sodium Channel|||Others

• Related Pathways:

  Others|||Membrane transporter/Ion channel

• Bioactivity:

  QAQ dichloride is a photoswitchable compound that blocks voltage-gated Na v and K v channels. Its channel-blocking activity is observed in the trans form of the azobenzene photoswitch, while the cis form does not exhibit this effect. This compound is membrane-impermeant and selectively enters pain-sensing neurons expressing endogenous import channels. QAQ dichloride functions as a light-sensitive analgesic and provides a valuable tool for investigating signaling mechanisms involved in acute and chronic pain [1] [2].

• Smiles:

  [N+](CC(NC1=CC=C(N=NC2=CC=C(NC(C[N+](CC)(CC)CC)=O)C=C2)C=C1)=O)(CC)(CC)CC

• Molecular Formula:

  C28H44N6O2

• Molecular Weight:

  496.69

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1204416-85-2