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QAQ dichloride

CAT: 0931-T24692-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T24692-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1204416-85-2
Target
Sodium Channel, Others
Related Pathways
Others, Membrane transporter/Ion channel
Bioactivity
QAQ dichloride is a photoswitchable compound that blocks voltage-gated Na v and K v channels. Its channel-blocking activity is observed in the trans form of the azobenzene photoswitch, while the cis form does not exhibit this effect. This compound is membrane-impermeant and selectively enters pain-sensing neurons expressing endogenous import channels. QAQ dichloride functions as a light-sensitive analgesic and provides a valuable tool for investigating signaling mechanisms involved in acute and chronic pain [1] [2].
Smiles
[N+](CC(NC1=CC=C(N=NC2=CC=C(NC(C[N+](CC)(CC)CC)=O)C=C2)C=C1)=O)(CC)(CC)CC
Molecular Formula
C28H44N6O2
Molecular Weight
496.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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