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Mivacurium (dichloride)

CAT: 0804-HY-B1700A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1700A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell[1][2][3].
CAS Number
106861-44-3
UNSPSC
12352005
Hazard Statement
H301
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mivacurium-dichloride.html
Purity
99.35
Solubility
DMSO : 250 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
O=C(OCCC[N+]1(C)[C@H](CC2=CC(OC)=C(OC)C(OC)=C2)C3=C(C=C(OC)C(OC)=C3)CC1)CC/C=C/CCC(OCCC[N+]4(C)[C@H](CC5=CC(OC)=C(OC)C(OC)=C5)C6=C(C=C(OC)C(OC)=C6)CC4)=O.[Cl-].[Cl-]
Molecular Formula
C58H80Cl2N2O14
Molecular Weight
1100.17
Precautions
P264-P270-P330-P405-P501
References & Citations
[1]Delu Che, et al. Mivacurium Induce Mast Cell Activation and Pseudo-Allergic Reactions via MAS-related G Protein Coupled receptor-X2. Cell Immunol. 2018 Oct;332:121-128.|[2]J E Caldwell. New Skeletal Muscle Relaxants. Int Anesthesiol Clin. Winter 1995;33 (1) :39-60.|[3]Matthias Paul, et al. The Potency of New Muscle Relaxants on Recombinant Muscle-Type Acetylcholine Receptors. Anesth Analg. 2002 Mar;94 (3) :597-603; table of contents.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched