DAD (dichloride)

• UNSPSC Description:

  DAD dichloride is a type of ion channel blocker that blocks voltage-gated potassium channels. DAD dichloride is a third-generation photoswitch that responds to visible light. DAD dichloride has the potential for restoring visual function[1].

• Target Antigen:

  Potassium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/dad-dichloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C[NH+](CC)CC)NC(C=C1)=CC=C1/N=N/C2=CC=C(N(CC)CC[NH+](CC)CC)C=C2.[Cl-].[Cl-]

• Molecular Weight:

  525.56

• References & Citations:

  [1]Laura Laprell, et al. Photopharmacological Control of Bipolar Cells Restores Visual Function in Blind Mice. J Clin Invest. 2017 Jun 30;127(7):2598-2611.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported