DAD (dichloride)

• Description :

  DAD dichloride is a type of ion channel blocker that blocks voltage-gated potassium channels. DAD dichloride is a third-generation photoswitch that responds to visible light. DAD dichloride has the potential for restoring visual function[1].

• UNSPSC :

  12352005

• Target :

  Potassium Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/dad-dichloride.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C[NH+](CC)CC)NC(C=C1)=CC=C1/N=N/C2=CC=C(N(CC)CC[NH+](CC)CC)C=C2.[Cl-].[Cl-]

• Molecular Formula :

  C26H42Cl2N6O

• Molecular Weight :

  525.56

• References & Citations :

  [1]Laura Laprell, et al. Photopharmacological Control of Bipolar Cells Restores Visual Function in Blind Mice. J Clin Invest. 2017 Jun 30;127 (7) :2598-2611.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported