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Obidoxime (dichloride)

CAT: 0804-HY-W011108-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W011108-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated[1].
CAS Number
114-90-9
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/obidoxime-dichloride.html
Purity
96.60
Solubility
DMSO : 1 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O/N=C/C1=CC=[N+](C=C1)COC[N+]2=CC=C(C=C2)/C=N/O.[Cl-].[Cl-]
Molecular Formula
C14H16Cl2N4O3
Molecular Weight
359.21
References & Citations
[1]Kassa J, et al. A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice.Toxicol Mech Methods. 2015 Mar;25 (3) :229-33.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE

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