(Z) -10-Hydroxynortriptyline

CAT: 0804-HY-100646A-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100646A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(Z) -10-Hydroxynortriptyline is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].
CAS Number
[47132-19-4]
UNSPSC
12352005
Hazard Statement
H302
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/z-10-hydroxy-nortriptyline.html
Purity
99.72
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1C2=CC=CC=C2/C(C3=CC=CC=C3C1)=C\CCNC
Molecular Formula
C19H21NO
Molecular Weight
279.38
Precautions
H302
References & Citations
[1]Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22 (4) :371-8.|[2]Shimoda K, et al. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology Information (US) ; 2012-2017 Mar 23.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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