(E) -10-Hydroxynortriptyline-d3

• Description:

  (E) -10-Hydroxynortriptyline-d3 is a deuterium labeled (E) -10-Hydroxy Nortriptyline. (E) -10-Hydroxy Nortriptyline is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].

• Product Name Alternative:

  E-10-OH-NT-d3

• UNSPSC:

  12352005

• Target:

  Drug Metabolite; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Purity:

  99.65

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1C2=CC=CC=C2/C(C3=CC=CC=C3C1)=C/CCNC([2H])([2H])[2H]

• Molecular Formula:

  C19H18D3NO

• Molecular Weight:

  282.39

• References & Citations:

  [1]Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22 (4) :371-8.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported