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(E) -10-Hydroxynortriptyline (maleate)

CAT: 0804-HY-100646Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-100646Size:1 Each
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Description
(E) -10-Hydroxynortriptyline maleate is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].
CAS Number
74853-74-0
UNSPSC
12352005
Hazard Statement
H302
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/e-10-hydroxy-nortriptyline-maleate.html
Solubility
10 mM in DMSO
Smiles
OC1C2=CC=CC=C2/C(C3=CC=CC=C3C1)=C/CCNC.O=C(O)/C=C\C(O)=O
Molecular Formula
C23H25NO5
Molecular Weight
395.46
Precautions
P264-P270-P330-P501
References & Citations
[1]Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22 (4) :371-8.|[2]Shimoda K, et al. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology Information (US) ; 2012-2017 Mar 23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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