Products for Research Use Only
RegisterLogin

MG-B-28

CAT: 0804-HY-159885Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-159885Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MG-B-28 is an inhibitor of BTLA-HVEM with an IC50 value of 906 nM. MG-B-28 promotes T-cell activation in a dose-dependent manner by blocking the BTLA-HVEM interaction[1].
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mg-b-28.html
Smiles
COC1=CC=C([C@@H](C#N)N2CCN(C(C(C3=C4C=CC=C3)=NN(C5=CC=CC=C5)C4=O)=O)CC2)C=C1
Molecular Formula
C28H25N5O3
Molecular Weight
479.53
References & Citations
[1]Abdel-Rahman S A, et al. Small molecules from antibody pharmacophores (SMAbPs) as a hit identification workflow for immune checkpoints[J]. Science Advances, 2024, 10 (42) : eadq5540.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-173311Cbl-b-IN-28
HY-163031MAO-B-IN-28
HY-N15010Kynapcin-28
HY-174816DHODH-IN-28
HY-N171028-Deoxonimbolide
HY-155431ICMT-IN-28
HY-114169-01WRG-28
HY-W686216-01VK-28
HY-151275ALK5-IN-28
HY-179138CYP51-IN-28

Alternative Products

CatalogName
T201695-01MG-B-28
GTR19261373-01MAO-B-IN-28
T206570-01Cbl-b-IN-28
RM-K211128-01Kukoamine B Impurity 28
6009/50B I09 50 mg
RC6821Carboxypeptidase B >100U, mg
RC6844Carboxypeptidase B >170U, mg
MBS352027-01B-Amyloid [1-28]
RC6848Carboxypeptidase B >250U, mg.
6009/10B I09 10 mg

Popular Products