MG-B-28

• Target:

  PDE|||Others|||Apoptosis

• Related Pathways:

  Metabolism|||Apoptosis|||Others

• Bioactivity:

  MG-B-28, a BTLA-HVEM inhibitor, demonstrates an IC50 value of 906 nM. It promotes T cell activation dose-dependently by inhibiting the interaction between BTLA and HVEM.

• Smiles:

  COC1=CC=C([C@@H](C#N)N2CCN(C(C(C3=C4C=CC=C3)=NN(C5=CC=CC=C5)C4=O)=O)CC2)C=C1

• Molecular Formula:

  C28H25N5O3

• Molecular Weight:

  479.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C