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MAO-B-IN-28

CAT: 0804-HY-163031Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163031Size:1 Each
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Description
MAO-B-IN-28 (compound 10e) is a potent hMAO-B inhibitor with an IC50 of 1.9±0.5 nM. MAO-B-IN-28 can be used as a candidate for neurodegenerative diseases research[1].
CAS Number
3028096-72-9
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mao-b-in-28.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2C=CC=C1)C(C3=CC(C4=CC=CC(C(F)(F)F)=C4)=NO3)=CS2(=O)=O
Molecular Formula
C19H10F3NO4S
Molecular Weight
405.35
References & Citations
[1]Pengbing Mi, et al. Discovery of C-3 isoxazole substituted thiochromone S, S-dioxide derivatives as potent and selective inhibitors for monoamine oxidase B (MAO-B) . European Journal of Medicinal Chemistry. 2024, 263, 115956.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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