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RP-220

CAT: 0013-GTR19144677-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19144677-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RP-220 is a peptide that targets the NLRP3 enzyme and exhibits anti-inflammatory and anti-apoptotic properties. It inhibits apoptosis of renal tubular epithelial cells caused by alkaline damage by activating the MAPK signaling pathway. In mouse models of acute kidney injury (AKI), RP-220 significantly reduces NLRP3 expression, macrophage infiltration, and renal tissue damage. Additionally, RP-220 is applicable in research on systemic lupus erythematosus (SLE) and its complication lupus nephritis (LN) .
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction
Molecular Weight
2308.61
Storage Conditions
-20°C
Notes
For research use only.

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