TL13-68

• Description :

  TL13-68 is a biotin-tagged version of SM1-71, and it can be used to research the mechanism of SM1-71[1].

• UNSPSC :

  12352005

• Target :

  FGFR; LIM Kinase (LIMK) ; MAP3K; Ribosomal S6 Kinase (RSK) ; Src

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; MAPK/ERK Pathway; Protein Tyrosine Kinase/RTK

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/tl13-68.html

• Purity :

  98.88

• Solubility :

  DMSO : 150 mg/mL (ultrasonic)

• Smiles :

  O=C1N[C@@H]2[C@H](CCCCC(NCCOCCOCCOCCN3CCN(CC3)C(C=C4)=CC=C4NC(N=C5NC6=C(C=CC=C6)NC(C=C)=O)=NC=C5Cl)=O)SC[C@@H]2N1

• Molecular Formula :

  C41H55ClN10O6S

• Molecular Weight :

  851.46

• References & Citations :

  [1]Du G, et, al. Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine. J Med Chem. 2020 Feb 27; 63 (4) : 1624-1641.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported