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EGFR-IN-68

CAT: 0804-HY-147997Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-147997Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-68 (Compound 8d) is a potent EGFR inhibitor with an IC50 of 0.33 μM. EGFR-IN-68 shows anticancer activity[1].
CAS Number
[2416925-03-4]
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-68.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(N2N=C(C3=CC=CC=C3)CC2/C=C/C4=CC=CC=C4)C=C1
Molecular Formula
C24H22N2O
Molecular Weight
354.44
References & Citations
[1]George RF, et al. Some 1,3,5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking. Bioorg Chem. 2020 Jun;99:103780.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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