HDAC6-IN-68

• Description :

  HDAC6-IN-68 is an HDAC6 inhibitor (IC50 = 118 nM) and a ligand for the target protein for PROTAC (HDAC6) . HDAC6-IN-68 can be used to synthesize PROTAC HDAC6 degrader 7 (HY-179421) [1].

• UNSPSC :

  12352005

• Target :

  HDAC; Ligands for Target Protein for PROTAC

• Related Pathways :

  Cell Cycle/DNA Damage; Epigenetics; PROTAC

• Field of Research :

  Inflammation/Immunology

• Smiles :

  O=C(C1=CC=C(CN2C3=CC=CC=C3C=CC4=C2C=CC=C4O)C=C1)NNCC

• Molecular Formula :

  C24H23N3O2

• Molecular Weight :

  385.46

• References & Citations :

  [1]Sun S, et al. Design, Synthesis, and Anti-inflammatory Activity Evaluation for Hydrazide-Based HDAC6 Targeted Protein Degraders. J Med Chem. 2025 Nov 27;68 (22) :24519-24545.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  HDAC6