PROTAC SMARCA2/4-degrader-10

PROTAC SMARCA2/4-degrader-10

• CAS Number: 2568277-33-6
• UNSPSC Description: PROTAC SMARCA2/4-degrader-10 (compound I-399) is a potent SMARCA2 degrader with an DC50 value of [1].
• Target Antigen: Epigenetic Reader Domain; PROTACs
• Type: Reference compound
• Related Pathways: Epigenetics;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-smarca2-4-degrader-10.html
• Smiles: NC1=C(C=C(C2=C(C=CC=C2)O)N=N1)C3=CN(C4CCN(CC4)CC[C@@H]5CC[C@H](CC5)C(N[C@@H](C(C)(C)C)C(N6[C@@H](C[C@H](C6)O)C(NCC7=CC=C(C8=C(N=CS8)C)C=C7)=O)=O)=O)N=C3
• Molecular Weight: 903.15
• References & Citations: [1]Nan Ji, et al. Smarca degraders and uses thereof. US20230072658A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported