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YSK 05

CAT: 0804-HY-147087-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-147087-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo[1].
CAS Number
[1318793-78-0]
UNSPSC
12352005
Hazard Statement
H225, H319
Target
Liposome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ysk-05.html
Purity
98.68
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN1CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)(OCCCCCCCC/C=C\C/C=C\CCCCC)CC1
Molecular Formula
C42H77NO2
Molecular Weight
628.07
Precautions
H225, H319
References & Citations
[1]Sato Y, et al. A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo. J Control Release. 2012 Nov 10;163 (3) :267-76.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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