CVM-05-002

• Description :

  CVM-05-002 is a PI5P4K inhibitor, with IC50 values of 0.27 μM and 1.7 μM for PI5P4Kα and PI5P4Kβ, respectively[1].

• UNSPSC :

  12352005

• Target :

  PI5P4K

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cvm-05-002.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CS(NC(C=C1)=CC=C1C2=CN=CC(/C=C3SC(NC\3=O)=N)=C2)(=O)=O

• Molecular Formula :

  C16H14N4O3S2

• Molecular Weight :

  374.44

• References & Citations :

  [1]Theresa D Manz, et al. Discovery and Structure-Activity Relationship Study of (Z) -5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. J Med Chem. 2020 May 14;63 (9) :4880-4895.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2428738-43-4]