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CVM-05-002

CAT: 0804-HY-153532Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-153532Size:1 Each
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Description
CVM-05-002 is a PI5P4K inhibitor, with IC50 values of 0.27 μM and 1.7 μM for PI5P4Kα and PI5P4Kβ, respectively[1].
CAS Number
[2428738-43-4]
UNSPSC
12352005
Target
PI5P4K
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cvm-05-002.html
Solubility
10 mM in DMSO
Smiles
CS(NC(C=C1)=CC=C1C2=CN=CC(/C=C3SC(NC\3=O)=N)=C2)(=O)=O
Molecular Formula
C16H14N4O3S2
Molecular Weight
374.44
References & Citations
[1]Theresa D Manz, et al. Discovery and Structure-Activity Relationship Study of (Z) -5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. J Med Chem. 2020 May 14;63 (9) :4880-4895.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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