KCC2G rabbit pAb

CAT: 0855-ES15352-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0855-ES15352-01Size:50 µL

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Background

The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca (2+) /calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.[provided by RefSeq, Mar 2011]

Description

The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca (2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined. [provided by RefSeq, Mar 2011],

UniProt

Q13555

Swiss Prot

Q13555

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human KCC2G AA range: 490-540

Target

KCC2G

Clonality

Polyclonal

Source

Rabbit

Applications

Concentration

1 mg/ml

Dilution

WB 1:500-2000

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Sarcoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side .

Gene ID (Human)

818

UniProtKB · Q13555

Calcium/calmodulin-dependent protein kinase type II subunit gamma

KCC2G_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q13555
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CAMK2G
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: CaM kinase II subunit gamma, CaMK-II subunit gamma
EC number: 2.7.11.17
Processing: —
Secondary accessions: A0A0A0MS52, A0A0A0MT11, O00561, O15378, Q13279, Q13282, Q13556, Q5SQZ3, Q5SQZ4, Q5SWX4, Q7KYX5, Q8N4I3, Q8NIA4

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Molecular function

Calmodulin-bindingDevelopmental proteinKinaseSerine/threonine-protein kinaseTransferase

Biological process

DifferentiationNeurogenesis

Disease

Intellectual disability

Cellular component

MembraneSarcoplasmic reticulum

PTM

Phosphoprotein

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