Garcinone E

• Description :

  Garcinone E is a natural xanthone found in the rind of the mangosteen fruit. Garcinone E induces apoptosis and inhibits cancer cell migration. Garcinone E has anticancer effects on different human cancer cell lines, including colorectal, breast, and hepatocellular carcinomas[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis

• Type :

  Natural Products

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/garcinone-e.html

• Purity :

  98.19

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C2=C(OC3=C1C(O)=C(C/C=C(C)\C)C(O)=C3)C(C/C=C(C)\C)=C(O)C(O)=C2C/C=C(C)\C

• Molecular Formula :

  C28H32O6

• Molecular Weight :

  464.55

• References & Citations :

  [1]Linli Yang, et al. Garcinone-E exhibits anticancer effects in HeLa human cervical carcinoma cells mediated via programmed cell death, cell cycle arrest and suppression of cell migration and invasion. AMB Express. 2020 Jul 16;10 (1) :126.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [112649-21-5]