Garcinone B

• Description :

  Garcinone B, a xanthone derivative, is a nature product that could be isolated from the pericarp of Mangosteen. Garcinone B is a potent ACE2 and Mpro inhibitor. Garcinone B can be used in research of COVID-19[1].

• CAS Number :

  [76996-28-6]

• UNSPSC :

  12352005

• Target :

  Angiotensin-converting Enzyme (ACE) ; SARS-CoV

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/garcinone-b.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC(C(C/C=C(C)/C)=C1O)=CC2=C1C(C3=C4C(OC(C)(C)C=C4)=C(O)C=C3O2)=O

• Molecular Formula :

  C23H22O6

• Molecular Weight :

  394.42

• References & Citations :

  [1]Suhandi C, et, al. for COVID-19 Treatment through Angiotensin-Converting Enzyme 2 and Main Protease Blockade: A Computational Study. Molecules. 2023 Jul 4;28 (13) :5187.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported