Garcinone B

• UNSPSC Description:

  Garcinone B, a xanthone derivative, is a nature product that could be isolated from the pericarp of Mangosteen. Garcinone B is a potent ACE2 and Mpro inhibitor. Garcinone B can be used in research of COVID-19[1].

• Target Antigen:

  Angiotensin-converting Enzyme (ACE); SARS-CoV

• Type:

  Natural Products

• Related Pathways:

  Anti-infection;Metabolic Enzyme/Protease

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/garcinone-b.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(C(C/C=C(C)/C)=C1O)=CC2=C1C(C3=C4C(OC(C)(C)C=C4)=C(O)C=C3O2)=O

• Molecular Weight:

  394.42

• References & Citations:

  [1]Suhandi C, et, al. for COVID-19 Treatment through Angiotensin-Converting Enzyme 2 and Main Protease Blockade: A Computational Study. Molecules. 2023 Jul 4;28(13):5187.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  76996-28-6