Garcinone B

• Description:

  Garcinone B, a xanthone derivative, is a nature product that could be isolated from the pericarp of Mangosteen. Garcinone B is a potent ACE2 and Mpro inhibitor. Garcinone B can be used in research of COVID-19[1].

• UNSPSC:

  12352005

• Target:

  Angiotensin-converting Enzyme (ACE) ; SARS-CoV

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/garcinone-b.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC (C (C/C=C (C) /C) =C1O) =CC2=C1C (C3=C4C (OC (C) (C) C=C4) =C (O) C=C3O2) =O

• Molecular Formula:

  C23H22O6

• Molecular Weight:

  394.42

• References & Citations:

  [1]Suhandi C, et, al. for COVID-19 Treatment through Angiotensin-Converting Enzyme 2 and Main Protease Blockade: A Computational Study. Molecules. 2023 Jul 4;28 (13) :5187.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  76996-28-6