DBCO-​C6-​acid

• UNSPSC Description:

  DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues[1]. DBCO- C6- acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• Target Antigen:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dbco-c6-acid.html

• Purity:

  98.39

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(CCCCC(O)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3

• Molecular Weight:

  333.387

• References & Citations:

  [1]Almaliti J, et al. Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1425485-72-8