DBCO-C3-Acid

• Description :

  DBCO-C3-Acid is a Click Chemistry intermediate used in the synthesis of antibody-drug conjugate (ADC) linker[1].

• UNSPSC :

  12352203

• Hazard Statement :

  H315, H319, H335

• Target :

  ADC Linker

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/dbco-c3-acid.html

• Purity :

  99.68

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(CCCC(O)=O)N1CC2=CC=CC=C2C#CC3=CC=CC=C31

• Molecular Formula :

  C20H17NO3

• Molecular Weight :

  319.36

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]van Geel R, et al. Chemoenzymatic Conjugation of Toxic Payloads to the Globally Conserved N-Glycan of Native mAbs Provides Homogeneous and Highly Efficacious Antibody-Drug Conjugates. Bioconjug Chem. 2015;26 (11) :2233-2242.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• CAS Number :

  [1207355-31-4]