DBCO-PEG3-acid

• UNSPSC Description:

  DBCO-PEG3-acid is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG3-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1].

• Target Antigen:

  ADC Linker

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dbco-peg3-acid.html

• Smiles:

  OC(CCOCCOCCOCCNC(CCC(N(C1)C2=C(C=CC=C2)C#CC3=C1C=CC=C3)=O)=O)=O

• Molecular Weight:

  508.56

• References & Citations:

  [1]Shih-Hsien Chuang, et al. Antibody-drug conjugates containing an anti-mesothelin antibody and uses thereof. WO2021248048A2.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2754384-59-1