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(±) 4-HDHA

CAT: 0804-HY-130289-01Size: 25 μg (2.90 mM x 25 μL in Methanol)Dry Ice: NoHazardous: No
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CAT#:0804-HY-130289-01Size:25 μg (2.90 mM x 25 μL in Methanol)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(±) 4-HDHA (4-Hydroxy docosahexaenoic acid) is an autoxidation product of Docosahexaenoic acid (DHA). (±) 4-HDHA is a PPARγ agonist, antidiabetic and anti-inflammatory agent[1][2].
CAS Number
90906-40-4
Product Name Alternative
4-Hydroxy docosahexaenoic acid; (±) 4-HDoHE
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/racemic-4-hdha.html
Concentration
2.90 mM * 25 μL in Methanol
Purity
99.05
Smiles
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C=C\C(O)CCC(O)=O
Molecular Formula
C22H32O3
Molecular Weight
344.49
Precautions
H302, H315, H319, H335
References & Citations
[1]Yamamoto K, et al. 4-Hydroxydocosahexaenoic acid, a potent peroxisome proliferator-activated receptor gamma agonist alleviates the symptoms of DSS-induced colitis. Biochem Biophys Res Commun. 2008 Mar 14;367 (3) :566-72. |[2]Richard Louis Dunbar, et al. Lymph-releasing compositions of fatty acids and uses thereof for lymphatic incorporation and systemic disease treatment. Patent. WO2023146984.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARγ