(±) 8-HDHA

• Description:

  (±) 8-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±) 8-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.

• Product Name Alternative:

  (±) 8-HDoHE; 8-hydroxy Docosahexaenoic acid; (±) 8-HDoHE

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/racemic-8-hdha.html

• Concentration:

  290.28 μM * 500 μL in Ethanol

• Purity:

  99.9

• Smiles:

  CC/C=C\C/C=C\C/C=C\C/C=C\CC(O)/C=C/C=C\CCC(O)=O

• Molecular Formula:

  C22H32O3

• Molecular Weight:

  344.49

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]VanRollins, et al. Autooxidation of docosahexaenoic acid: Analysis of ten isomers of hydroxydocosahexaenoate. J. Lipid Res. 25 (5), 507-517 (1984) .

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Solution, -20°C, 2 years

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [90780-54-4]