(±) 17-HDHA

CAT: 0931-MF-0035673Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0035673Size:1 mg
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CAS Number
90780-52-2
Target
Others
Related Pathways
Others
Bioactivity
(±) 17-HDHA is an autoxidation product of docosahexaenoic acid in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. 17 (S) -HDHA could be produced by enzymatic oxidation of DHA using soybean lipoxygenase (LO) and is the putative product of mammalian 15-LOs. 17 (S) -HDHA was shown to be an inhibitor of U-46619 -induced rabbit and rat aortic smooth muscle contraction with IC50 values of 4.9 and 7.2 ?M, respectively. (±) 17-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
Smiles
CC\C=C/CC(O)\C=C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O
Molecular Formula
C22H32O3
Molecular Weight
344.495
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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