(±) 17-HDHA

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  (±) 17-HDHA is an autoxidation product of docosahexaenoic acid in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. 17 (S) -HDHA could be produced by enzymatic oxidation of DHA using soybean lipoxygenase (LO) and is the putative product of mammalian 15-LOs. 17 (S) -HDHA was shown to be an inhibitor of U-46619 -induced rabbit and rat aortic smooth muscle contraction with IC50 values of 4.9 and 7.2 ?M, respectively. (±) 17-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.

• Smiles :

  CC\C=C/CC(O)\C=C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O

• Molecular Formula :

  C22H32O3

• Molecular Weight :

  344.495

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  90780-52-2