(±) 14-HDHA

• Target :

  Drug Metabolite|||Endogenous Metabolite

• Related Pathways :

  Metabolism

• Bioactivity :

  (±) 14-HDHA is a hydroxydocosahexaenoic acid, an oxidized metabolite of DHA generated intracellularly by enzymatic or non-enzymatic reactions, is one of the specific substrates of 15-PGDH and can be further oxidized to the anti-inflammatory 14-oxoDHA, and in primary alveolar macrophages, 14-HDoHE itself significantly inhibits LPS-induced IL-6 mRNA expression in primary alveolar macrophages, which may be relevant to inflammatory diseases such as asthma.

• Smiles :

  C(\C(C/C=C\C/C=C\CC)O)=C/C=C\C/C=C\C/C=C\CCC(O)=O

• Molecular Formula :

  C22H32O3

• Molecular Weight :

  344.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  87042-40-8